Foundation for Dementia Protection: Researchers identify a diet that safeguards our brain against the onset of the disease.

A recent study from the University of California has revealed that the ketogenic diet (keto diet) — a high-fat, low-carbohydrate diet — may play a significant role in delaying the early symptoms of Alzheimer’s disease. Known for its effectiveness in treating epilepsy and aiding weight loss, the keto diet appears to impact cognitive health by altering brain cell interactions, potentially postponing the onset of the disease in at-risk individuals, according to Surrey Live.

Researcher Gino Cortopassi, a professor of biomolecular sciences and author of a paper published in the journal Communications Biology, noted that the findings support the notion that diet, particularly the molecule beta-hydroxybutyrate (BHB) produced during ketosis, may help delay mild cognitive impairment and possibly Alzheimer’s disease, though it is not a definitive cure.

The keto diet, which emphasizes a high intake of fats, a moderate amount of protein, and minimal carbohydrates, has gained widespread popularity for its benefits that extend beyond weight loss, including potential protection of our cognitive functions. Previous studies have also hinted at increased lifespan: mice on a ketogenic diet showed a 13% increase in longevity. The new research by the scientists was based on these findings.

Over seven months, the diet was tested on animal models of Alzheimer’s disease and demonstrated improvements in memory and neuronal adaptability (synaptic plasticity), which are crucial for cognitive health. These changes were associated with a marked increase in circulating BHB levels, particularly in female subjects during fasting periods.

The results pointed to BHB as a key component of the potential cognitive benefits of the diet. During ketosis, with low carbohydrate intake and the body using fats as fuel, BHB levels rise, and this metabolite may enhance brain function by supporting memory storage mechanisms. In mice on the keto diet, these mechanisms, often disrupted by Alzheimer’s disease, significantly recovered. If these benefits prove helpful for humans, the keto diet could become a practical dietary intervention for slowing the progression of Alzheimer’s symptoms, especially for those showing early signs of cognitive decline, the authors believe.

Alzheimer’s disease is a leading cause of dementia, affecting around a million people in the UK alone. Given that current treatments have limited effectiveness, the potential for dietary interventions is promising for many. Despite the encouraging results, Cortopassi emphasized that the keto diet should not be viewed as a standalone solution, but rather as a potentially valuable addition to existing disease prevention strategies.

The keto diet, originally developed for epilepsy patients, is described by the NHS as a high-fat diet with controlled protein intake and very low carbohydrates. Common foods include healthy fats (such as avocados and olive oil), protein sources (like meat and fish), and low-carb vegetables. However, such a diet requires strict adherence, eliminating high-carbohydrate foods like grains, sugar, and starchy vegetables, which can be challenging and lead to side effects.

As scientific interest in the cognitive benefits of dietary approaches grows, further research is expected to clarify the precise role of diet in preventing Alzheimer’s disease and how BHB and other metabolic byproducts may contribute to long-term brain health. This could be particularly vital in the context of the global rise in dementia cases, the authors stated.

Important! This article is based on the latest scientific and medical research and is in line with them. The text is for informational purposes only and does not contain medical advice. For diagnosis, please consult a physician.